Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.59 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.59 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.59 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.49 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.49 |
| ▸ | AMD1 | P17707 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068884 | 0.88 | PI4KA (0.58) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL16256552 | 0.86 | PI4KA (0.78) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL20133912 | 0.86 | PI4KA (0.65) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL16579246 | 0.82 | RXFP1 (0.58) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL12379161 | 0.82 | RXFP1 (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL16020541 | 0.82 | RXFP1 (0.70) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL20133914 | 0.81 | PI4KA (0.57) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL16256549 | 0.80 | RXFP1 (0.56) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL16256553 | 0.79 | RXFP1 (0.55) | PI4KAPI4K2BPI4K2API4KBRXFP1 | |
| SCHEMBL13400312 | 0.78 | PI4KA (0.53) | PI4KAPI4K2BPI4K2API4KBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008111082-A1 | PROCESS FOR THE SYNTHESIS OF IB-MECA | CAN-FITE BIOPHARMA LTD. (IL) | 2008-09-18 | — | — | WO | disclosed |