Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | PI4KA | P42356 | 1/20 | 0.55 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.55 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.55 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.55 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 3/20 | 0.53 |
| ▸ | AMD1 | P17707 | 2/20 | 0.44 |
| ▸ | MARS1 | P56192 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | AHCY | P23526 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16256549 | 0.92 | RXFP1 (0.56) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16579246 | 0.90 | RXFP1 (0.58) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16256552 | 0.82 | PI4KA (0.78) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL16020541 | 0.82 | RXFP1 (0.70) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL12379161 | 0.82 | RXFP1 (0.70) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1798145 | 0.81 | RXFP1 (0.57) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL15426673 | 0.80 | ADORA2A (0.51) | RXFP1 | |
| SCHEMBL20133912 | 0.80 | PI4KA (0.65) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL14068882 | 0.79 | PI4KA (0.59) | RXFP1PI4KAPI4K2BPI4K2API4KB | |
| SCHEMBL1796855 | 0.79 | RXFP1 (0.57) | RXFP1PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895530-B2 | Method of reducing intraocular pressure in humans | INOTEK PHARMACEUTICALS CORPORATION (US) | 2014-11-25 | — | — | US | disclosed |