Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 4/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 5/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.40 |
| ▸ | HPGDS | O60760 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | RARA | P10276 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13410019 | 0.88 | S1PR1 (0.46) | S1PR2S1PR1S1PR3S1PR4ALDH1A1 | |
| SCHEMBL13444577 | 0.85 | HPGDS (0.55) | TP53ACKR3HPGDSALDH1A1MEN1 | |
| SCHEMBL13410015 | 0.84 | MMP2 (0.44) | S1PR2S1PR1S1PR3S1PR4ALDH1A1 | |
| SCHEMBL13409976 | 0.82 | S1PR2 (0.53) | S1PR2S1PR1S1PR3S1PR4RARB | |
| Trifluoroacetic Acid SCHEMBL3683180 | 0.81 | S1PR1 (0.41) | S1PR2S1PR1S1PR3S1PR4 | |
| Trifluoroacetic Acid SCHEMBL3683187 | 0.81 | S1PR1 (0.41) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL14070566 | 0.80 | SUCNR1 (0.48) | S1PR2S1PR1S1PR3S1PR4RARB | |
| Trifluoroacetic Acid SCHEMBL3683485 | 0.79 | MMP2 (0.41) | S1PR2S1PR1S1PR3S1PR4 | |
| Trifluoroacetic Acid SCHEMBL3683491 | 0.79 | MMP2 (0.41) | S1PR2S1PR1S1PR3S1PR4 | |
| SCHEMBL13410039 | 0.77 | S1PR1 (0.46) | S1PR2S1PR1S1PR3S1PR4RARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |