Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 6/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.36 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.36 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | IRS1 | P35568 | 1/20 | 0.36 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3683180 | 0.93 | S1PR1 (0.41) | S1PR1S1PR2S1PR3S1PR4CASP3 | |
| Trifluoroacetic Acid SCHEMBL3683187 | 0.93 | S1PR1 (0.41) | S1PR1S1PR2S1PR3S1PR4CASP3 | |
| SCHEMBL14823019 | 0.89 | S1PR1 (0.47) | S1PR1S1PR2S1PR3S1PR4ALDH1A1 | |
| SCHEMBL13444028 | 0.88 | CASP3 (0.43) | CASP3TAS1R3TAS1R1ITGB3ITGA2B | |
| SCHEMBL14070155 | 0.88 | S1PR2 (0.46) | S1PR1S1PR2S1PR3S1PR4ALDH1A1 | |
| SCHEMBL3683184 | 0.84 | FAAH (0.35) | S1PR1S1PR2S1PR3S1PR4TAS1R3 | |
| SCHEMBL13410015 | 0.84 | MMP2 (0.44) | S1PR1S1PR2S1PR3S1PR4ALDH1A1 | |
| SCHEMBL13410017 | 0.82 | CASP3 (0.34) | ALDH1A1CASP3TAS1R3TAS1R1ITGB3 | |
| SCHEMBL13409976 | 0.82 | S1PR2 (0.53) | S1PR1S1PR2S1PR3S1PR4ALDH1A1 | |
| SCHEMBL13410039 | 0.81 | S1PR1 (0.46) | S1PR1S1PR2S1PR3S1PR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8410150-B2 | Inhibitors of carnitine palmitoyltransferase and treating cancer | UNIVERSITY HEALTH NETWORK (CA) | 2013-04-02 | — | — | US | disclosed |
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK | 2010-04-29 | — | — | US | disclosed |
| WO-2008109991-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | UNIVERSITY HEALTH NETWORK (CA) | 2008-09-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105900-A1 | INHIBITORS OF CARNITINE PALMITOYLTRANSFERASE AND TREATING CANCER | CPT1A, CPT1B, CPT2 | S1PR1 400/4885S1PR2 413/4885S1PR3 493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.