SCHEMBL1407108

SCHEMBL1407108

CC/C(=C/N(C)C)C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 1/20 0.36
CYP2C9 P11712 1/20 0.34
GRIK1 P39086 3/20 0.32
GRIK2 Q13002 3/20 0.32
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3288026 1.00 FFAR3 (0.36) FFAR3CYP2C9GRIK1GRIK2KDM4E
SCHEMBL526367 1.00 FFAR3 (0.36) FFAR3CYP2C9GRIK1GRIK2KDM4E
Hydrochloric Acid SCHEMBL28125142 0.98 FFAR3 (0.35) FFAR3CYP2C9GRIK1GRIK2KDM4E
Chloromethane SCHEMBL10773493 0.95 FFAR3 (0.33) FFAR3CYP2C9GRIK1GRIK2TDP1
Sulfuric Acid SCHEMBL28124682 0.91 FFAR3 (0.31) FFAR3CYP2C9
SCHEMBL2417580 0.86 FFAR3 (0.33) FFAR3CYP2C9
SCHEMBL20819419 0.82
SCHEMBL876069 0.81 HDAC3 (0.40) FFAR3CYP2C9GRIK1GRIK2TSHR
SCHEMBL7636206 0.81 FFAR3 (0.33) FFAR3GRIK1GRIK2
SCHEMBL4544359 0.80 TDP1 (0.36) FFAR3CYP2C9TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2707367-B1 METHODS FOR PREPARING NAPHTHYRIDINES BIONOMICS LTD (AU) 2019-10-09 EP claimed
US-20250214998-A1 CYCLIC COMPOUNDS AS RECEPTOR MODULATING THERAPEUTICS AND METHODS AND USES THEREOF BIONOMICS LTD (AU) 2025-07-03 US disclosed
US-12275732-B2 Cyclic compounds as receptor modulating therapeutics and methods and uses thereof BIONOMICS LIMITED (AU) 2025-04-15 US disclosed
EP-3867252-B1 6-INDAN-2-YLOXY-3-(MORPHOLINE-4-CARBONYL)-1,8-NAPHTHYRIDIN-4-ONE DERIVATIVES AND SIMILAR COMPOUNDS AS MODULATORS OF THE ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR FOR THE TREATMENT OF ANXIETY BIONOMICS LTD (AU) 2023-12-06 EP disclosed
US-20230286981-A1 Imidazo[4,5-c]quinolin-2-one Compounds and Their Use in Treating Cancer ASTRAZENECA AB (SE) 2023-09-14 US disclosed
US-11613539-B2 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer ASTRAZENECA AB (SE) 2023-03-28 US disclosed
US-20220409629-A1 BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION PFIZER INC. 2022-12-29 US disclosed
EP-4048665-A1 BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION Reviral Limited (GB) 2022-08-31 EP disclosed
EP-3683220-B1 8-[6-[3-(AMINO)PROPOXY]-3-PYRIDYL]-1-ISOPROPYL-IMIDAZO[4,5-C]QUINOLIN-2-ONE DERIVATIVES AS SELECTIVE MODULATORS OF ATAXIA TELANGIECTASIA MUTATED (ATM) KINASE FOR THE TREATMENT OF HUNTINGTON'S DISEASE ASTRAZENECA AB (SE) 2022-04-13 EP disclosed
US-20210355124-A1 Cyclic compounds as receptor modulating therapeutics and methods and uses thereof BIONOMICS LIMITED (AU) 2021-11-18 US disclosed
US-20020192601-A1 Process for the production of film having refractive index distribution MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-12-19 US disclosed
EP-0882049-B1 POSSIBLY SUBSTITUTED 8-CYANO-1-CYCLOPROPYL-7-(2,8-DIAZABICYCLO- 4.3.0]-NONAN-8-YL)-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLIN CARBOXYLIC ACIDS AND THEIR DERIVATIVES BAYER AG (DE) 2002-11-20 EP disclosed
EP-1255616-A2 PROCESS FOR THE PRODUCTION OF STRONGLY ADHERENT SURFACE-COATINGS BY PLASMA-ACTIVATED GRAFTING Ciba SC Holding AG (CH) 2002-11-13 EP disclosed
EP-1215202-A1 Intermediates for the preparation of possibly substituted 8-cyano-1-cyclopropyl-7-(2,8-diazabicyclo-(4.3.0)-nonan-8-yl)-6-fluoro-1,4-dihydro-4-oxo-3-quinolin carboxylic acids and their derivatives BAYER AG (DE) 2002-06-19 EP disclosed
WO-2001058971-A2 PROCESS FOR THE PRODUCTION OF STRONGLY ADHERENT SURFACE-COATINGS BY PLASMA-ACTIVATED GRAFTING CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2001-08-16 WO disclosed
EP-0882049-A1 POSSIBLY SUBSTITUTED 8-CYANO-1-CYCLOPROPYL-7-(2,8-DIAZABICYCLO- 4.3.0]-NONAN-8-YL)-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLIN CARBOXYLIC ACIDS AND THEIR DERIVATIVES BAYER AG (DE) 1998-12-09 EP disclosed
EP-0503958-B1 Heterocyclic compounds and their production NIPPON PAINT CO LTD (JP) 1998-09-23 EP disclosed
WO-1997031001-A1 POSSIBLY SUBSTITUTED 8-CYANO-1-CYCLOPROPYL-7-(2,8-DIAZABICYCLO-[4.3.0]-NONAN-8-YL)-6-FLUORO-1,4-DIHYDRO-4-OXO-3-QUINOLIN CARBOXYLIC ACIDS AND THEIR DERIVATIVES BAYER AKTIENGESELLSCHAFT (DE) 1997-08-28 WO disclosed
US-5496943-A USING UNSATURATED ACYLISOCYANATE COMPOUNDS TO FORM OXAZOLINES, PYRANS WITH AMINOCARBONYLHETERO SUBSTITUTION AND GLUTARIMIDE DERIVATIVES AS CHEMICAL INTERMEDIATES NIPPON PAINT CO., LTD. (JP) 1996-03-05 US disclosed
EP-0503958-A2 Heterocyclic compounds and their production Nippon Paint Co., Ltd. (JP) 1992-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220409629-A1 BENZODIAZEPINE DERIVATIVES FOR TREATING A RESPIRATORY SYNCYTIAL VIRUS (RSV) INFECTION GABRA1, GABRA3, CNR1 FFAR3 204/4885CYP2C9 525/4885GRIK1 570/4885
US-20250214998-A1 CYCLIC COMPOUNDS AS RECEPTOR MODULATING THERAPEUTICS AND METHODS AND USES THEREOF CHRNA7, CHRNA5, CHRNA1 FFAR3 403/4885CYP2C9 1995/4885GRIK1 87/4885
US-12275732-B2 Cyclic compounds as receptor modulating therapeutics and methods and uses thereof CHRNA7, CHRNA1, CHRNA5 FFAR3 403/4885CYP2C9 1938/4885GRIK1 89/4885
US-11613539-B2 Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer ATM, BRCA1, CHEK2 FFAR3 3868/4885CYP2C9 1487/4885GRIK1 3171/4885
US-20210355124-A1 Cyclic compounds as receptor modulating therapeutics and methods and uses thereof CHRNA7, CHRNA1, CHRNA5 FFAR3 403/4885CYP2C9 1938/4885GRIK1 89/4885
US-20230286981-A1 Imidazo[4,5-c]quinolin-2-one Compounds and Their Use in Treating Cancer ATM, BRCA1, CHEK2 FFAR3 3868/4885CYP2C9 1487/4885GRIK1 3171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.