SCHEMBL876069

SCHEMBL876069

CCCC(=CN(C)C)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.40
HDAC1 Q13547 4/20 0.40
HDAC2 Q92769 4/20 0.40
HDAC8 Q9BY41 4/20 0.40
FFAR3 O14843 3/20 0.40
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ALDH1A1 P00352 4/20 0.33
TSHR P16473 4/20 0.33
GRIK1 P39086 3/20 0.32
GRIK2 Q13002 2/20 0.32
CYP2C9 P11712 1/20 0.32
AKR1B1 P15121 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
PPARG P37231 4/20 0.30
PPARD Q03181 4/20 0.30
PPARA Q07869 4/20 0.30
GPR84 Q9NQS5 3/20 0.30
HDAC11 Q96DB2 3/20 0.30
TDP1 Q9NUW8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1772976 0.87 ALDH1A1 (0.45) CES2CES1ALDH1A1TSHRAKR1B1
SCHEMBL9319567 0.85 AKR1B1 (0.46) CES2CES1ALDH1A1TSHRCYP2C9
SCHEMBL499749 0.84 GPR84 (0.48) CES2CES1ALDH1A1TSHRCYP2C9
SCHEMBL25053314 0.83 FFAR3 (0.37) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL9821243 0.82
SCHEMBL1407108 0.81 FFAR3 (0.36) FFAR3ALDH1A1TSHRGRIK1GRIK2
SCHEMBL3288026 0.81 FFAR3 (0.36) FFAR3ALDH1A1TSHRGRIK1GRIK2
SCHEMBL526367 0.81 FFAR3 (0.36) FFAR3ALDH1A1TSHRGRIK1GRIK2
SCHEMBL423119 0.80 CES2 (0.35) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL2900266 0.80 CES2 (0.35) HDAC3HDAC1HDAC2HDAC8FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2823283-B1 SORPTION OF WATER FROM A SAMPLE USING A POLYMERIC DRYING AGENT DIONEX CORP (US) 2023-04-19 EP claimed
EP-2557924-B1 DERMAL PHARMACEUTICAL COMPOSITIONS OF 1-METHYL-2',6'-PIPECOLOXYLIDIDE AND METHOD OF USE RELMADA THERAPEUTICS INC (US) 2019-06-12 EP claimed
EP-1558202-B1 WATER SOLUBLE MONOMERS AND POLYMERS FOR PROTECTING SUBTRATES FROM ULTRAVIOLET LIGHT NALCO CO (US) 2016-11-16 EP claimed
US-7795360-B2 Terpolymer of an alkoxysilylalkyl (meth)acrylate, a tris(trialkylsiloxy)silylalkyl (meth)acrylate, and another unsaturated monomer, such as an alkyl (meth)acrylate, and a condensation-reaction accelerating catalyst; excellent storage stability before curing; water- and oilproof coating of high hardness DOW CORNING TORAY COMPANY, LTD. (JP) 2010-09-14 US claimed
EP-1642946-B1 COATING AGENT COMPOSITION DOW CORNING TORAY CO LTD (JP) 2009-04-22 EP claimed
EP-1419897-B1 Ink jet recording material AGFA GEVAERT (BE) 2007-06-27 EP claimed
EP-1436338-B1 FLUORINATED COPOLYMERS FOR HYDROPHOBIC AND OLOEPHOBIC TREATMENT OF BUILDING MATERIALS DU PONT (US) 2006-05-03 EP claimed
EP-1150661-B1 TOPICAL SPRAYS COMPRISING A FILM FORMING COMPOSITION CIPLA LTD (IN) 2003-10-22 EP claimed
EP-0633390-B1 Set retarding cement additive HALLIBURTON ENERGY SERV INC (US) 1999-09-15 EP claimed
EP-0482027-B1 POLYMERIC THICKENERS AND METHODS OF PRODUCING THE SAME JOHNSON & SON INC S C (US) 1994-11-09 EP claimed
EP-0179921-B1 BASE MATERIAL HAVING A DYED SURFACE FILM AND DYEING METHOD NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1990-08-08 EP claimed
EP-0201342-B1 HAIR-CONDITIONING RESIN COMPOSITIONS MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-08-01 EP claimed
EP-3710415-A1 CURABLE ORGANOPOLYSILOXANE COMPOSITIONS Wacker Chemie AG (DE) 2020-09-23 EP disclosed
EP-2618918-B1 MEMBRANE HAVING A PORE-FREE SEPARATION LAYER, AND ALSO USE AND METHOD FOR PRODUCTION OF A MEMBRANE SULZER CHEMTECH AG (CH) 2018-10-31 EP disclosed
EP-3155030-A1 POLYURETHANES WITH REDUCED ALDEHYDE EMISSION BASF SE (DE) 2017-04-19 EP disclosed
WO-2015189095-A1 POLYURETHANES WITH REDUCED ALDEHYDE EMISSION BASF SE (DE) 2015-12-17 WO disclosed
EP-0415055-A2 Water-soluble pressure-sensitive skin adhesive RÖHM GMBH (DE) 1991-03-06 EP disclosed
EP-0379892-A2 Binder for water-borne gloss paints Röhm GmbH (DE) 1990-08-01 EP disclosed
EP-0373439-A2 Process for controlling particle size in the preparation of polymers in powder form BASF Aktiengesellschaft (DE) 1990-06-20 EP disclosed
EP-0307816-A2 Process for improving the printability of paper BASF Aktiengesellschaft (DE) 1989-03-22 EP disclosed