SCHEMBL14071602

SCHEMBL14071602

CCCCCCCCCC(=O)N(C(C)=O)c1ccc(S(=O)(=O)O)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 1/20 0.40
ALDH1A1 P00352 4/20 0.39
HTT P42858 1/20 0.39
TP53 P04637 1/20 0.38
CA2 P00918 4/20 0.38
CA1 P00915 3/20 0.38
CA12 O43570 2/20 0.38
CA4 P22748 2/20 0.38
CA5A P35218 2/20 0.38
CA7 P43166 2/20 0.38
CA9 Q16790 2/20 0.38
CA13 Q8N1Q1 2/20 0.38
CA14 Q9ULX7 2/20 0.38
THRB P10828 2/20 0.38
THRA P10827 1/20 0.38
CES2 O00748 4/20 0.37
CES1 P23141 4/20 0.37
PTGES O14684 2/20 0.37
ALOX5 P09917 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14071608 1.00 S1PR3 (0.40) S1PR3ALDH1A1HTTTP53CA2
SCHEMBL14071604 0.81 CNR2 (0.53) ALDH1A1HTT
SCHEMBL14071609 0.81 NPC1 (0.50) ALDH1A1HTTTP53CES2CES1
SCHEMBL14071605 0.77 CNR2 (0.35) CES2CES1
SCHEMBL8376731 0.77 S1PR3 (0.42) S1PR3ALDH1A1HTTTP53CA2
SCHEMBL9402363 0.75 KMT2A (0.38) ALDH1A1HTTTP53
SCHEMBL9402358 0.75 KMT2A (0.38) ALDH1A1HTTTP53
SCHEMBL3177450 0.74 HSD17B3 (0.57) ALDH1A1HTTTP53
SCHEMBL28974747 0.74 ALDH1A1 (0.52) S1PR3ALDH1A1HTTCA2CA1
2-Tridecanone SCHEMBL11077384 0.74 LMNA (0.53) S1PR3ALDH1A1HTTTP53CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7425527-B2 Organic activator THE PROCTER & GAMBLE COMPANY (US) 2008-09-16 US disclosed