Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HSD17B3 | P37058 | 8/20 | 0.53 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.43 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.43 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.43 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.43 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.43 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.43 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.43 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.43 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.43 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.43 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.43 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28974747 | 0.88 | ALDH1A1 (0.52) | LMNAS1PR3KDM4EALDH1A1HTT | |
| 2-Decanone SCHEMBL10627920 | 0.86 | TSHR (0.52) | S1PR3ALDH1A1PTGS2 | |
| Phenolsulfonic Acid SCHEMBL27415090 | 0.79 | LMNA (0.77) | LMNAHSD17B3ESR1ALDH1A1TP53 | |
| Phenolsulfonic Acid SCHEMBL8086594 | 0.78 | LMNA (0.53) | LMNAHSD17B3ESR1ESR2S1PR3 | |
| SCHEMBL10497062 | 0.78 | HSD17B3 (0.65) | HSD17B3CA2 | |
| SCHEMBL28422360 | 0.78 | HSD17B3 (0.65) | HSD17B3CA2 | |
| Sulfuric Acid SCHEMBL29144513 | 0.77 | CES2 (0.54) | ESR1ALDH1A1HSD17B10 | |
| SCHEMBL27549029 | 0.76 | HSD17B3 (0.63) | HSD17B3CA2 | |
| SCHEMBL6463892 | 0.76 | HSD17B3 (0.63) | HSD17B3CA2 | |
| Octanoic Acid SCHEMBL11772394 | 0.76 | GPR84 (0.55) | HSD17B3ESR1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489091-A | ESTERASE AND ANTIBODY INHIBITORS | TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) | 1984-12-18 | — | — | US | disclosed |
| US-4411911-A | Method of treating hyperlipidemia and inflammation with sulfonate derivatives | TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-10-25 | — | — | US | disclosed |