Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL334049 | 0.91 | TP53 (0.42) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL334048 | 0.84 | ALOX5 (0.44) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL334022 | 0.84 | MEN1 (0.44) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL333747 | 0.84 | MEN1 (0.43) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL333921 | 0.83 | PTGS2 (0.50) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL333584 | 0.82 | PTGES (0.49) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL333739 | 0.81 | KMT2A (0.62) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL335074 | 0.79 | TP53 (0.44) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL333628 | 0.79 | MEN1 (0.42) | TP53MAPTTHRBMEN1KMT2A | |
| SCHEMBL333844 | 0.78 | MEN1 (0.45) | TP53MAPTTHRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2011-03-09 | — | — | EP | disclosed |