Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1407297 | 0.95 | KDM4E (0.40) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL333969 | 0.85 | MAPT (0.40) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL333957 | 0.82 | MAPT (0.42) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL334112 | 0.80 | MAPT (0.61) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL333970 | 0.80 | MEN1 (0.39) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL368313 | 0.80 | MAPT (0.39) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL335008 | 0.79 | PTGES (0.49) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL333448 | 0.79 | ROCK2 (0.43) | MAPTHTTMAPK1HPGDPKM | |
| SCHEMBL333599 | 0.79 | LMNA (0.50) | MAPTHTTPPARGPPARA | |
| SCHEMBL333737 | 0.79 | PPARG (0.45) | MAPTHTTMAPK1HPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841735-B1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2011-03-09 | — | — | EP | disclosed |