Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | PARP1 | P09874 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 5/20 | 0.51 |
| ▸ | MMP13 | P45452 | 5/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | HTR1B | P28222 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073359 | 0.88 | TSHR (0.63) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14073344 | 0.85 | TSHR (0.55) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14073579 | 0.83 | KMT2A (0.60) | ALDH1A1MAPTUSP2POLBBLM | |
| SCHEMBL14073306 | 0.82 | USP2 (0.59) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14073392 | 0.82 | TSHR (0.56) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14073276 | 0.82 | TSHR (0.66) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14072985 | 0.81 | TSHR (0.85) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14073338 | 0.81 | TSHR (0.64) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14073152 | 0.81 | TSHR (0.59) | TSHRMAOAPARP1ALDH1A1MMP8 | |
| SCHEMBL14073336 | 0.81 | TSHR (0.67) | TSHRMAOAPARP1ALDH1A1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | TSHR 4343/4885MAOA 137/4885PARP1 327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.