Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 5/20 | 0.47 |
| ▸ | MMP13 | P45452 | 5/20 | 0.47 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14072985 | 0.85 | TSHR (0.85) | TSHRALDH1A1MAOAPOLBPARP1 | |
| SCHEMBL14073421 | 0.85 | TSHR (0.68) | TSHRALDH1A1MAOAPARP1GAA | |
| SCHEMBL14073342 | 0.85 | TSHR (0.64) | TSHRALDH1A1MAOAPOLBPARP1 | |
| SCHEMBL14073412 | 0.83 | TSHR (0.68) | TSHRALDH1A1MAOAPARP1GAA | |
| SCHEMBL14073593 | 0.83 | MAPT (0.58) | TSHRALDH1A1POLBGAAMAPT | |
| SCHEMBL14073033 | 0.82 | TSHR (0.76) | TSHRALDH1A1MAOAPARP1GAA | |
| SCHEMBL14073241 | 0.82 | TSHR (0.67) | TSHRALDH1A1MAOAPARP1GAA | |
| SCHEMBL14073398 | 0.81 | TSHR (0.68) | TSHRALDH1A1MAOAPARP1GAA | |
| SCHEMBL14073276 | 0.80 | TSHR (0.66) | TSHRALDH1A1MAOAPARP1GAA | |
| SCHEMBL16861502 | 0.80 | TSHR (0.58) | TSHRALDH1A1MAOAPARP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | TSHR 4343/4885ALDH1A1 714/4885MAOA 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.