Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 7/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14073716 | 0.92 | GRM4 (0.51) | KMT2AMALT1GRM4TRPV1CYP2C9 | |
| SCHEMBL14073561 | 0.87 | KMT2A (0.58) | KMT2AMALT1MAPTALDH1A1TRPV1 | |
| SCHEMBL14073451 | 0.85 | KMT2A (0.68) | KMT2AMALT1MAPTALDH1A1TRPV1 | |
| SCHEMBL14073156 | 0.82 | TSHR (0.58) | KMT2AALDH1A1POLB | |
| SCHEMBL14073568 | 0.82 | KMT2A (0.67) | KMT2AMALT1MAPTALDH1A1GRM4 | |
| SCHEMBL14073592 | 0.82 | KMT2A (0.69) | KMT2AMALT1MAPTALDH1A1TRPV1 | |
| SCHEMBL14073585 | 0.81 | KMT2A (0.60) | KMT2AMALT1MAPTALDH1A1TRPV1 | |
| SCHEMBL14073610 | 0.80 | KMT2A (0.67) | KMT2AMALT1MAPTALDH1A1TRPV1 | |
| SCHEMBL14073478 | 0.79 | KMT2A (0.62) | KMT2AMALT1MAPTALDH1A1TRPV1 | |
| SCHEMBL14073480 | 0.79 | KMT2A (0.62) | KMT2AMALT1MAPTALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | ALANTOS PHARMACEUTICALS HOLDING, INC. | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221093-A1 | Metalloprotease inhibitors containing a heterocyclic moiety | MMP12, MMP13, MMP25 | KMT2A 2900/4885MALT1 4139/4885MAPT 3986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.