SCHEMBL14074635

SCHEMBL14074635

CCO[Si](CCCNC(=O)OCc1c2ccccc2cc2ccccc12)(OCC)OCC

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.47
HTT P42858 1/20 0.40
NCEH1 Q6PIU2 1/20 0.39
KEAP1 Q14145 2/20 0.38
NFE2L2 Q16236 2/20 0.38
HDAC1 Q13547 2/20 0.38
HDAC2 Q92769 2/20 0.38
HDAC3 O15379 1/20 0.38
HDAC4 P56524 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC11 Q96DB2 1/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
HDAC9 Q9UKV0 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
FAAH O00519 1/20 0.38
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23228332 0.85 EPHX1 (0.53) EPHX1HTTNCEH1TSHR
SCHEMBL30821051 0.84 EPHX1 (0.56) EPHX1HTTNCEH1KEAP1NFE2L2
SCHEMBL18412607 0.84 EPHX1 (0.56) EPHX1HTTNCEH1KEAP1NFE2L2
SCHEMBL9609737 0.83 HTT (0.43) HTTNCEH1KEAP1NFE2L2HDAC1
SCHEMBL25763415 0.83 EPHX1 (0.51) EPHX1NCEH1FAAH
SCHEMBL2397727 0.82 EPHX1 (0.55) EPHX1HTTNCEH1LMNAALDH1A1
SCHEMBL9609731 0.81 TGM2 (0.47) HTTKEAP1NFE2L2HDAC1HDAC2
SCHEMBL13399559 0.81 EPHX1 (0.49) EPHX1HTTNCEH1KEAP1NFE2L2
SCHEMBL16317577 0.81 EPHX1 (0.51) EPHX1HTTKEAP1NFE2L2HIF1A
SCHEMBL16131330 0.81 ALDH1A1 (0.41) HTTNCOR2CYP1A2ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814527-B2 Three-dimensional printing with supramolecular templated hydrogels TRUSTEES OF DARTMOUTH COLLEGE (US) 2023-11-14 US disclosed
US-20200131383-A1 THREE-DIMENSIONAL PRINTING WITH SUPRAMOLECULAR TEMPLATED HYDROGELS TRUSTEES OF DARTMOUTH COLLEGE (US) 2020-04-30 US disclosed
US-7427678-B2 Method for immobilizing oligonucleotides employing the cycloaddition bioconjugation method SIGMA-ALDRICH CO. (US) 2008-09-23 US disclosed