Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 16/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 15/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.38 |
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14075334 | 0.87 | OPRK1 (0.34) | OPRM1OPRK1OPRD1OGFRL1 | |
| SCHEMBL14075212 | 0.87 | OPRK1 (0.34) | OPRM1OPRK1OPRD1 | |
| SCHEMBL14075146 | 0.85 | OPRK1 (0.43) | OPRM1OPRK1OPRD1 | |
| SCHEMBL14075147 | 0.83 | OPRK1 (0.33) | OPRM1OPRK1OPRD1 | |
| SCHEMBL13752445 | 0.76 | OPRM1 (0.35) | OPRM1OPRK1OPRD1OGFRL1 | |
| SCHEMBL14075329 | 0.73 | OPRM1 (0.34) | OPRM1OPRK1OPRD1 | |
| SCHEMBL13849236 | 0.72 | OPRK1 (0.44) | OPRM1OPRK1OPRD1 | |
| SCHEMBL14075337 | 0.72 | OPRM1 (0.35) | OPRM1OPRK1OPRD1 | |
| SCHEMBL14075213 | 0.71 | OPRM1 (0.35) | OPRM1OPRK1OPRD1 | |
| SCHEMBL14075208 | 0.71 | OPRM1 (0.34) | OPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080234306-A1 | N-Oxides of 4,5-Epoxy-Morphinanium Analogs | PROGENICS PHARMACEUTICALS, INC. (US) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234306-A1 | N-Oxides of 4,5-Epoxy-Morphinanium Analogs | OPRM1, OPRD1, OPRK1 | OPRM1 1/4885OPRK1 3/4885OPRD1 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.