Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.32 |
| ▸ | CACNG8 | Q8WXS5 | 2/20 | 0.32 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10052628 | 0.82 | ACHE (0.36) | FFAR4 | |
| SCHEMBL13484249 | 0.81 | FFAR4 (0.38) | FFAR4RAPGEF4 | |
| SCHEMBL12889451 | 0.80 | CYP11B1 (0.39) | PDK2 | |
| SCHEMBL14424434 | 0.76 | FFAR4 (0.42) | FFAR4RAPGEF4PDK2 | |
| SCHEMBL12889580 | 0.76 | — | — | |
| SCHEMBL12889549 | 0.76 | — | — | |
| SCHEMBL14075240 | 0.76 | RAPGEF4 (0.34) | RAPGEF4PDK2 | |
| SCHEMBL14075238 | 0.74 | RAPGEF4 (0.50) | RAPGEF4 | |
| SCHEMBL13087003 | 0.74 | RAPGEF4 (0.38) | RAPGEF4 | |
| SCHEMBL4567627 | 0.73 | ALOX5AP (0.39) | FFAR4PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419706-B2 | Liquid crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-09-02 | — | — | US | disclosed |