SCHEMBL13484249

SCHEMBL13484249

Cc1cc(C)c(OC(F)(F)F)c(F)c1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.38
RAPGEF4 Q8WZA2 6/20 0.34
AR P10275 1/20 0.34
GPR3 P46089 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10052628 0.89 ACHE (0.36) FFAR4GPR3KDM4E
SCHEMBL14424434 0.87 FFAR4 (0.42) FFAR4RAPGEF4ARGPR3KDM4E
SCHEMBL14075239 0.81 FFAR4 (0.35) FFAR4RAPGEF4
SCHEMBL17733010 0.78 NOTUM (0.31) AR
SCHEMBL26382463 0.77 PDE2A (0.36) FFAR4
SCHEMBL24749508 0.76 AR (0.39) AR
SCHEMBL17662618 0.76 ACHE (0.46) RAPGEF4
SCHEMBL14525521 0.74
SCHEMBL14328236 0.74 FFAR4 (0.31) FFAR4GPR3
SCHEMBL16790936 0.73 SCN10A (0.35) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7658978-B2 Liquid crystalline medium MERCK PATENT GESELLSCHAFT (DE) 2010-02-09 US disclosed
US-20090230354-A1 Liquid Crystalline Medium MERCK PATENT GESELLSCHAFT (DE) 2009-09-17 US disclosed