Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.50 |
| ▸ | ITGAV | P06756 | 7/20 | 0.50 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | MC4R | P32245 | 11/20 | 0.47 |
| ▸ | MC5R | P33032 | 11/20 | 0.47 |
| ▸ | MC3R | P41968 | 11/20 | 0.47 |
| ▸ | MC1R | Q01726 | 11/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14262562 | 0.95 | KEAP1 (0.43) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14075719 | 0.91 | ITGB3 (0.54) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14075722 | 0.91 | ITGB3 (0.50) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14075695 | 0.90 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14262476 | 0.87 | MC4R (0.38) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14075647 | 0.87 | ITGB3 (0.49) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14075652 | 0.87 | ITGB3 (0.49) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14075724 | 0.87 | ITGB3 (0.49) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14075705 | 0.87 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5KEAP1 | |
| SCHEMBL14262530 | 0.87 | ITGB3 (0.46) | ITGB3ITGAVITGB1ITGA5KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | SIEMENS MEDICAL SOLUTIONS USA, INC. | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213175-A1 | Click chemistry-derived cyclic peptidomimetics as integrin markers | ITGB1, ITGAM, ITGB3 | ITGB3 3/4885ITGAV 8/4885ITGB1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.