Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MSR1 | P21757 | 1/20 | 0.55 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19772656 | 0.71 | ICMT (0.37) | MSR1CYP1A2CYP2C19RAB9ANPC1 | |
| SCHEMBL16079453 | 0.71 | DDAH1 (0.41) | CYP1A2RAB9ANPC1SMN1; SMN2ALOX15 | |
| SCHEMBL17519501 | 0.70 | MAPT (0.38) | CYP1A2CYP2C19RAB9ANPC1RXFP1 | |
| SCHEMBL16071181 | 0.70 | MAPT (0.38) | CYP1A2CYP2C19RAB9ANPC1RXFP1 | |
| SCHEMBL10500123 | 0.69 | KAT2A (0.41) | RAB9ANPC1SMN1; SMN2ALOX15TSHR | |
| SCHEMBL10592292 | 0.67 | MAPT (0.40) | CYP1A2CYP2C19RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL16079437 | 0.67 | APP (0.38) | RAB9ANPC1ALOX5SMN1; SMN2MAPT | |
| SCHEMBL14075827 | 0.67 | MSR1 (0.43) | MSR1SRCPTPN1TSHRKDM4E | |
| SCHEMBL9813146 | 0.66 | SMN1; SMN2 (0.46) | RAB9ANPC1RXFP1SMN1; SMN2ALOX15 | |
| SCHEMBL28421922 | 0.65 | CSNK1D (0.59) | RAB9ANPC1SMN1; SMN2TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080214606-A1 | Methods for the Identification and Use of Compounds Suitable for the Treatment of Drug Resistant Cancer Cells | The Government of the United States of America as represented by The Secretary of the Dept. of ..... (US) | 2008-09-04 | — | — | US | disclosed |
| US-20080214606-A1 | Methods for the Identification and Use of Compounds Suitable for the Treatment of Drug Resistant Cancer Cells | The Government of the United States of America as represented by The Secretary of the Dept. of ..... (US) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080214606-A1 | Methods for the Identification and Use of Compounds Suitable for the Treatment of Drug Resistant Cancer Cells | ABCC1, MCL1, DLD | MSR1 2914/4885LOXL2 2677/4885SRC 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.