Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.38 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.37 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19342205 | 0.91 | KDM4E (0.48) | LMNACA2CA4CA5AP4HTM | |
| SCHEMBL21503934 | 0.83 | LDHA (0.36) | LMNACA2CA4CA5AMEN1 | |
| SCHEMBL11991137 | 0.82 | NPC1 (0.40) | P4HTMP4HA1PTPN1 | |
| SCHEMBL18253841 | 0.81 | PTPN2 (0.38) | LMNACA2CA4CA5APTPN2 | |
| SCHEMBL18253854 | 0.81 | LMNA (0.34) | LMNACA2CA4CA5AMEN1 | |
| SCHEMBL21066301 | 0.80 | LMNA (0.42) | LMNACA2CA4CA5AMEN1 | |
| SCHEMBL18253783 | 0.79 | LMNA (0.33) | LMNACA2CA4CA5AMEN1 | |
| SCHEMBL5436616 | 0.79 | LMNA (0.60) | LMNACA2CA4CA5AMEN1 | |
| SCHEMBL5439069 | 0.79 | LMNA (0.60) | LMNACA2CA4CA5AMEN1 | |
| SCHEMBL132983 | 0.79 | LMNA (0.60) | LMNACA2CA4CA5AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7419728-B2 | Light-emitting device containing bis-phosphineoxide compound | EASTMAN KODAK COMPANY (US) | 2008-09-02 | — | — | US | disclosed |
| US-7419728-B2 | Light-emitting device containing bis-phosphineoxide compound | EASTMAN KODAK COMPANY (US) | 2008-09-02 | — | — | US | disclosed |