Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 16/20 | 0.77 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | CDK9 | P50750 | 1/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14096401 | 0.87 | CSF1R (1.00) | CSF1R | |
| SCHEMBL20855958 | 0.72 | SRPK1 (0.74) | — | |
| SCHEMBL29868850 | 0.72 | SRPK1 (0.74) | — | |
| SCHEMBL14096152 | 0.69 | CSF1R (0.73) | CSF1RPOLBATM | |
| SCHEMBL13439367 | 0.68 | CSF1R (1.00) | CSF1R | |
| SCHEMBL14385081 | 0.68 | CSF1R (0.69) | CSF1R | |
| SCHEMBL13405655 | 0.68 | CSF1R (0.75) | CSF1RPOLBATM | |
| SCHEMBL5202289 | 0.67 | CSF1R (1.00) | CSF1R | |
| SCHEMBL13405640 | 0.67 | CSF1R (1.00) | CSF1R | |
| SCHEMBL31157980 | 0.67 | CSF1R (1.00) | CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7427683-B2 | c-fms kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-09-23 | — | — | US | disclosed |
| US-7427683-B2 | c-fms kinase inhibitors | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-09-23 | — | — | US | disclosed |