Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6990199 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| SCHEMBL6990202 | 1.00 | CHRM2 (0.41) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| Hydrochloric Acid SCHEMBL2419739 | 0.98 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| Hydrochloric Acid SCHEMBL2419742 | 0.98 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| SCHEMBL6556633 | 0.89 | ALDH1A1 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| SCHEMBL5167294 | 0.89 | ALDH1A1 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| SCHEMBL5108694 | 0.89 | ALDH1A1 (0.46) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| Hydrochloric Acid SCHEMBL15329263 | 0.87 | ALDH1A1 (0.49) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| Hydrochloric Acid SCHEMBL5471959 | 0.87 | ALDH1A1 (0.49) | CHRM2CHRM1CHRM4CHRM3CHRNA7 | |
| Hydrochloric Acid SCHEMBL2491331 | 0.87 | ALDH1A1 (0.49) | CHRM2CHRM1CHRM4CHRM3CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221330-A1 | Mutilin-Derivative Substituted at Position 12 | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
| US-20080221330-A1 | Mutilin-Derivative Substituted at Position 12 | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221330-A1 | Mutilin-Derivative Substituted at Position 12 | MRPL21, MRPL37, AARS1 | CHRM2 4637/4885CHRM1 4413/4885CHRM4 4818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.