Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 6/20 | 0.50 |
| ▸ | AURKA | O14965 | 2/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 1/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CDK7 | P50613 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544791 | 0.92 | MAPT (0.57) | PTK2AURKAMAPK8AURKBMAPT | |
| SCHEMBL14079358 | 0.89 | MAPT (0.63) | PTK2AURKAMAPK8MAPTALOX15 | |
| SCHEMBL14079362 | 0.86 | PTK2 (0.46) | PTK2AURKAMAPTALOX15KDM4E | |
| SCHEMBL14079360 | 0.84 | MAPT (0.49) | PTK2AURKAMAPTALOX15KDM4E | |
| SCHEMBL7852387 | 0.82 | MAPT (0.71) | AURKAMAPK8AURKBMAPTALOX15 | |
| SCHEMBL4544815 | 0.82 | CDC25B (0.57) | AURKAMAPK8AURKBMAPTKDM4E | |
| SCHEMBL4544793 | 0.80 | MAPT (0.77) | PTK2AURKAMAPK8MAPTALOX15 | |
| SCHEMBL4544804 | 0.77 | PTK2 (0.52) | PTK2AURKAMAPTALOX15KDM4E | |
| SCHEMBL4544820 | 0.75 | KDM4E (0.60) | MAPTKDM4EPOLBKCNH3NFKB1 | |
| SCHEMBL4544795 | 0.74 | MAPT (0.58) | PTK2AURKAMAPTALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080192192-A1 | Optical film and polarizing plate | FUJIFILM CORPORATION (JP) | 2008-08-14 | — | — | US | disclosed |