SCHEMBL4544815

SCHEMBL4544815

CCOC(=O)c1ccccc1Nc1nc(Nc2cccc(C)c2)nc(Nc2cccc(C)c2)n1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 7/20 0.57
CDC25A P30304 1/20 0.57
CDC25C P30307 1/20 0.57
SMN1; SMN2 Q16637 2/20 0.55
KDM4E B2RXH2 1/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
MAPT P10636 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
AURKA O14965 1/20 0.54
MAPK8 P45983 1/20 0.54
AURKB Q96GD4 1/20 0.54
TP53 P04637 3/20 0.50
HPGD P15428 1/20 0.50
METTL3 Q86U44 1/20 0.47
SIRT5 Q9NXA8 1/20 0.47
TSHR P16473 1/20 0.47
POLB P06746 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544791 0.89 MAPT (0.57) KDM4EMAPTAURKAMAPK8AURKB
SCHEMBL4544856 0.89 CDC25B (0.60) CDC25BCDC25ACDC25CSMN1; SMN2KDM4E
SCHEMBL4544865 0.82 MEN1 (0.67) CDC25BSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL14079359 0.82 PTK2 (0.50) KDM4EMAPTAURKAMAPK8AURKB
SCHEMBL4544845 0.81 MEN1 (0.70) CDC25BSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL4544778 0.81 MEN1 (0.70) CDC25BSMN1; SMN2KDM4ENPC1RAB9A
SCHEMBL4544868 0.80 MEN1 (0.67) SMN1; SMN2KDM4ENPC1RAB9AMAPT
SCHEMBL4544782 0.78 NFKB1 (0.54) SMN1; SMN2NPC1RAB9AMAPTL3MBTL1
SCHEMBL26742261 0.78 HTT (0.56) SMN1; SMN2KDM4ENPC1RAB9AMAPT
SCHEMBL7852387 0.78 MAPT (0.71) KDM4EMAPTAURKAMAPK8AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9223070-B2 Optical film, polarizing plate equipped with the optical film, process for manufacture of the polarizing plate, and liquid crystal display device Konica Minolta, Inc. (JP) 2015-12-29 US disclosed
US-20150253480-A1 RETARDATION FILM, ELONGATED CIRCULARLY POLARIZING PLATE AND ORGANIC EL DISPLAY PRODUCED USING SAID RETARDATION FILM Konica Minolta, Inc. (JP) 2015-09-10 US disclosed
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-9103988-B2 Liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-08-11 US disclosed
US-8976325-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2015-03-10 US disclosed
US-8947621-B2 Liquid crystal display device comprising a front plate having a lamda/4 plate that includes a hard coat layer and method for manufacturing the same KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2015-02-03 US disclosed
US-8681295-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2014-03-25 US disclosed
US-20130293812-A1 OPTICAL FILM, POLARIZING PLATE EQUIPPED WITH THE OPTICAL FILM, PROCESS FOR MANUFACTURE OF THE POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE Konica Minolta, Inc. (JP) 2013-11-07 US disclosed
US-20130169897-A1 METHOD FOR MANUFACTURING LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE WITH FRONT PLATE KONICA MINOLTA ADVANCED LAYERS, INC. (JP) 2013-07-04 US disclosed
US-8477273-B2 VA-mode liquid-crystal display device FUJIFILM CORPORATION (JP) 2013-07-02 US disclosed
US-20080204644-A1 Liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-28 US disclosed
US-20080198303-A1 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-08-21 US disclosed
US-20080192192-A1 Optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-08-14 US disclosed
US-20080174724-A1 Liquid crystal display device, optical film and polarizing plate FUJIFILM CORPORATION (JP) 2008-07-24 US disclosed
US-20080158488-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-07-03 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080137014-A1 Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed
WO-2007023990-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJI FILM CORPORATION (JP) 2007-03-01 WO disclosed