SCHEMBL1407987

SCHEMBL1407987

O=S(=O)(O)OS(=O)(=O)Oc1ccccn1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.35
KDM4E B2RXH2 3/20 0.35
P4HTM Q9NXG6 2/20 0.35
CYP1A2 P05177 2/20 0.35
POLB P06746 1/20 0.35
CCR1 P32246 1/20 0.35
CCR5 P51681 1/20 0.35
CCR8 P51685 1/20 0.35
METAP1 P53582 1/20 0.35
BLM P54132 1/20 0.35
HIF1A Q16665 1/20 0.35
DOHH Q9BU89 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
TSHR P16473 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NAPRT Q6XQN6 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
COMT P21964 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1407984 0.89 KDM4E (0.41) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL3857735 0.85 LMNA (0.41) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL6512183 0.85 KDM4E (0.44) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL28313514 0.78 KDM4E (0.38) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL28588858 0.78 LMNA (0.38) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL29211934 0.77 P4HTM (0.40) LMNAKDM4EP4HTMCYP1A2POLB
Dipyridyl SCHEMBL7209625 0.77 KDM4E (0.58) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL1360826 0.73 LMNA (0.41) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL6220452 0.73 TDP1 (0.43) LMNAKDM4EP4HTMCYP1A2POLB
SCHEMBL23611463 0.72 KDM4E (0.39) LMNAKDM4EP4HTMCYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116801734-A Green closed-loop biowaste refining process for producing intelligent active extracts and delivery system for its use 塞拉治疗有限责任公司 2023-09-22 CN disclosed
EP-4149563-A1 PEPTIDIC SCAFFOLDS, PROCESSES FOR MANUFACTURING THE SAME, AND USES THEREOF AS SOLUBLE SUPPORTS Synhelix (FR) 2023-03-22 EP disclosed
EP-1002066-B1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIV UTAH RES FOUND (US) 2011-03-09 EP disclosed
US-7208299-B2 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces UNIVERSTIY OF UTAH RESEARCH FOUNDATION (US) 2007-04-24 US disclosed
EP-1002066-A4 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIV UTAH RES FOUND (US) 2004-12-01 EP disclosed
US-20040170964-A1 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces NAGLER, RICHARD, MR. 2004-09-02 US disclosed
US-6670199-B2 Adsorbing an end group activated block polymer on a hydrophobic surface; conjugating a biomolecule to the polymer; contacting with an organism or molecule, e.g. a cell, virus, antibody, to be adhered to the coated surface UNIVERSITY OF UTAH RESEARCH FOUNDATION 2003-12-30 US disclosed
US-20020019037-A1 Composition and method for regulating the adhesion of cells and biomolecules to hydrophobic surfaces NAGLER, RICHARD, MR. 2002-02-14 US disclosed
US-6284503-B1 ACTIVATING THE END GROUP OF AN ETHYLENE OXIDE-PROPYLENE OXIDE COPOLYMER, ADSORBTION OF THE COPOLYMER ON THE SURFACE, CONJUGATING A THIOL CONTAINING BIOMOLECULE TO THE COPOLYMER AND CONTACTING WITH CELL OR VIRUS TO ADHERE IT UNIVERSITY OF UTAH RESEARCH FOUNDATION 2001-09-04 US disclosed
EP-1002066-A1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2000-05-24 EP disclosed
WO-1998031734-A1 COMPOSITION AND METHOD FOR REGULATING THE ADHESION OF CELLS AND BIOMOLECULES TO HYDROPHOBIC SURFACES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 1998-07-23 WO disclosed