Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | P2RY10 | O00398 | 4/20 | 0.41 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17833014 | 0.88 | LMNA (0.58) | FABP3ALDH1A1ADRA1ALMNAESR1 | |
| SCHEMBL13619237 | 0.88 | LMNA (0.58) | FABP3ALDH1A1ADRA1ALMNAESR1 | |
| SCHEMBL21631754 | 0.86 | LMNA (0.67) | RECQLADRA1ALMNAESR1ADORA3 | |
| SCHEMBL2602822 | 0.83 | FABP3 (0.48) | FABP3ALDH1A1RECQLLMNAP2RY10 | |
| SCHEMBL27966574 | 0.82 | RECQL (0.59) | FABP3ALDH1A1RECQLLMNAAKT1 | |
| SCHEMBL28240661 | 0.82 | LMNA (0.47) | FABP3RECQLADRA1ALMNAESR1 | |
| SCHEMBL14080920 | 0.82 | FABP3 (0.61) | FABP3ADRA1ALMNAESR1ADORA3 | |
| SCHEMBL60848 | 0.81 | LMNA (0.70) | FABP3ALDH1A1ADRA1ALMNAESR1 | |
| SCHEMBL905581 | 0.81 | LMNA (0.70) | FABP3ALDH1A1ADRA1ALMNAESR1 | |
| SCHEMBL14447816 | 0.81 | LMNA (0.70) | FABP3ALDH1A1ADRA1ALMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408075-B1 | Synthesis of phosphocholine ester derivatives and conjugates thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-08-05 | — | — | US | disclosed |
| US-20080175852-A1 | SYNTHESIS OF PHOSPHOCHOLINE ESTER DERIVATIVES AND CONJUGATES THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080175852-A1 | SYNTHESIS OF PHOSPHOCHOLINE ESTER DERIVATIVES AND CONJUGATES THEREOF | PHOSPHO1, SGMS1, SGMS2 | FABP3 1691/4885ALDH1A1 3630/4885RECQL 3803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.