Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 1/20 | 0.61 |
| ▸ | P2RY10 | O00398 | 8/20 | 0.49 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.48 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CDC25A | P30304 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14448112 | 0.90 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL26061597 | 0.87 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL26018724 | 0.87 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL25665820 | 0.87 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL14758262 | 0.87 | FABP3 (0.70) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL3631867 | 0.86 | FABP3 (0.72) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL3629744 | 0.86 | FABP3 (0.72) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL3630629 | 0.86 | FABP3 (0.72) | FABP3P2RY10GPR34SMN1; SMN2NR5A2 | |
| SCHEMBL9630534 | 0.83 | ADRA2A (0.67) | FABP3SMN1; SMN2ADRA1ALMNAMAPT | |
| SCHEMBL13619237 | 0.83 | LMNA (0.58) | FABP3SMN1; SMN2ADRA1ALMNAESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408075-B1 | Synthesis of phosphocholine ester derivatives and conjugates thereof | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-08-05 | — | — | US | disclosed |
| US-20080175852-A1 | SYNTHESIS OF PHOSPHOCHOLINE ESTER DERIVATIVES AND CONJUGATES THEREOF | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080175852-A1 | SYNTHESIS OF PHOSPHOCHOLINE ESTER DERIVATIVES AND CONJUGATES THEREOF | PHOSPHO1, SGMS1, SGMS2 | FABP3 1691/4885P2RY10 2577/4885GPR34 1232/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.