Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17058218 | 0.87 | ALDH1A1 (0.31) | NPBWR1MCHR1 | |
| SCHEMBL17057972 | 0.82 | POLB (0.33) | — | |
| SCHEMBL17058559 | 0.81 | POLB (0.33) | NPBWR1 | |
| SCHEMBL11944458 | 0.80 | MAPT (0.36) | — | |
| SCHEMBL17058535 | 0.80 | SMN1; SMN2 (0.35) | — | |
| SCHEMBL17058289 | 0.80 | NPBWR1 (0.34) | NPBWR1MCHR1 | |
| SCHEMBL17057833 | 0.79 | NPBWR1 (0.32) | NPBWR1MCHR1 | |
| SCHEMBL17058174 | 0.79 | POLB (0.34) | — | |
| SCHEMBL17057853 | 0.78 | SMN1; SMN2 (0.35) | NPBWR1MCHR1 | |
| SCHEMBL17057817 | 0.78 | SMN1; SMN2 (0.38) | NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |