Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 7/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17057821 | 0.89 | POLB (0.38) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL17057920 | 0.89 | MCHR1 (0.37) | NPBWR1MCHR1SMN1; SMN2SLC2A1SLC2A3 | |
| SCHEMBL17058260 | 0.87 | POLB (0.41) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL14899749 | 0.85 | SMN1; SMN2 (0.45) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL14081539 | 0.83 | ALDH1A1 (0.42) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL17058316 | 0.82 | SLC2A1 (0.35) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL17058437 | 0.82 | ALDH1A1 (0.40) | NPBWR1MCHR1SMN1; SMN2SLC2A1SLC2A3 | |
| SCHEMBL17058072 | 0.82 | MCHR1 (0.36) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL11944036 | 0.82 | ALDH1A1 (0.48) | NPBWR1MCHR1POLBSMN1; SMN2LMNA | |
| SCHEMBL11945607 | 0.81 | HTR1A (0.38) | NPBWR1MCHR1SMN1; SMN2LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008115381-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS GLUCAN SYNTHASE INHIBITORS | SCHERING CORPORATION (US) | 2008-09-25 | — | — | WO | disclosed |