Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408234 | 1.00 | ANPEP (0.57) | ANPEPMEN1KMT2ATDP1DNM1 | |
| SCHEMBL12696613 | 0.84 | ANPEP (0.61) | ANPEPMEN1KMT2ATDP1DNM1 | |
| SCHEMBL421959 | 0.82 | EPHX1 (0.61) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL421960 | 0.82 | EPHX1 (0.61) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL20237224 | 0.82 | ANPEP (0.54) | ANPEPMEN1KMT2ATDP1DNM1 | |
| SCHEMBL11121889 | 0.81 | EPHX1 (0.59) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL25343744 | 0.80 | MEN1 (0.52) | ANPEPMEN1KMT2ATDP1DNM1 | |
| SCHEMBL3079282 | 0.78 | DNM1 (0.57) | ANPEPMEN1KMT2ATDP1DNM1 | |
| SCHEMBL10533348 | 0.78 | DNM1 (0.57) | ANPEPMEN1KMT2ATDP1DNM1 | |
| SCHEMBL359137 | 0.78 | ANPEP (0.50) | ANPEPMEN1KMT2ATDP1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1000952-B1 | New 2-halogenated derivatives of 5-O-deosaminylerythronolide A, process for making them as well as their use as medicines | AVENTIS PHARMA SA (FR) | 2011-03-09 | — | — | EP | disclosed |
| US-RE39743-E1 | 2-halogenated derivatives of 5-0 desosaminyl-erythronolide a, their preparation process and their antibiotic use | AVENTIS PHARMA S.A. (FR) | 2007-07-24 | — | — | US | disclosed |
| US-7119180-B2 | 2-halogenated derivatives of 5-O-desosaminyl-erythronolide A, their preparation process and their antibiotic use | AVENTIS PHARMA S.A. (FR) | 2006-10-10 | — | — | US | disclosed |
| US-20050065101-A1 | 2-Halogenated derivatives of 5-O-desosaminyl-erythronolide a, their preparation process and their antibiotic use | AVENTIS PHARMA S.A. (FR) | 2005-03-24 | — | — | US | disclosed |
| US-20020111319-A1 | 2-halogenated derivatives of 5-0-desosaminyl-erythronolide A, their preparation process and their antibiotic use | AGOURIDAS CONSTANTIN (FR) | 2002-08-15 | — | — | US | disclosed |
| US-6352983-B1 | ANTIBIOTICS AND BACTERICIDES | AVENTIS PHARMA S.A. (FR) | 2002-03-05 | — | — | US | disclosed |
| EP-1000952-A2 | New 2-halogenated derivatives of 5-O-deosaminylerythronolide A, process for making them as well as their use as medicines | HOECHST MARION ROUSSEL (FR) | 2000-05-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065101-A1 | 2-Halogenated derivatives of 5-O-desosaminyl-erythronolide a, their preparation process and their antibiotic use | EEF1D, GALE, DCTD | ANPEP 393/4885MEN1 2840/4885KMT2A 1720/4885 |
| US-20020111319-A1 | 2-halogenated derivatives of 5-0-desosaminyl-erythronolide A, their preparation process and their antibiotic use | EEF1D, GALE, EBPL | ANPEP 427/4885MEN1 2229/4885KMT2A 2291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.