Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13308431 | 0.90 | ANPEP (0.47) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL8351906 | 0.87 | CSNK1E (0.50) | ANPEPMAOA | |
| SCHEMBL13884907 | 0.83 | LMNA (0.58) | CYP2D6DNM1 | |
| SCHEMBL5023438 | 0.81 | ANPEP (0.49) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL20417941 | 0.80 | ALDH1A1 (0.47) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL22052987 | 0.80 | ALDH1A1 (0.47) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL20237224 | 0.79 | ANPEP (0.54) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL421959 | 0.79 | EPHX1 (0.61) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL421960 | 0.79 | EPHX1 (0.61) | ANPEPMEN1KMT2ATDP1BCHE | |
| SCHEMBL15101698 | 0.79 | DNM1 (0.53) | ANPEPMEN1KMT2ATDP1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013211-B1 | PURINE DERIVATIVES FOR USE AS ADENOSIN A2A RECEPTOR AGONISTS | NOVARTIS AG (CH) | 2012-03-14 | — | — | EP | disclosed |