SCHEMBL1408264

SCHEMBL1408264

OB(O)OOc1ccccc1.[NaH]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
LTA4H P09960 3/20 0.39
TSHR P16473 1/20 0.39
CA5A P35218 2/20 0.37
CA5B Q9Y2D0 2/20 0.37
CA4 P22748 2/20 0.36
CA6 P23280 1/20 0.36
CA7 P43166 1/20 0.36
ENPP2 Q13822 1/20 0.36
CA14 Q9ULX7 1/20 0.36
PCSK9 Q8NBP7 1/20 0.36
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
NR1H2 P55055 1/20 0.36
BAX Q07812 1/20 0.36
TAAR1 Q96RJ0 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276215 0.97 CA1 (0.43) CA1CA2LTA4HTSHRCA5A
Boric Acid SCHEMBL10871300 0.95 CA1 (0.41) CA1CA2LTA4HTSHRCA5A
SCHEMBL29140215 0.82 CA1 (0.43) CA1CA2LTA4HTSHRCA5A
SCHEMBL624916 0.76 TRPV6 (0.44) CA1CA2LTA4HTSHRCA5A
SCHEMBL3898221 0.76 LTA4H (0.45) CA1CA2LTA4HTSHRCA5A
SCHEMBL27847049 0.74 LTA4H (0.56) CA1CA2LTA4HTSHRCA5A
SCHEMBL187418 0.74 CA1 (0.44) CA1CA2LTA4HTSHRCA5A
SCHEMBL14905 0.71 LTA4H (0.60) CA1CA2LTA4HTSHRCA5A
SCHEMBL78440 0.70 CA1 (0.46) CA1CA2LTA4HTSHRCA5A
SCHEMBL28337059 0.70 CA1 (0.46) CA1CA2LTA4HTSHRCA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2937372-B1 A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-22 EP claimed
EP-2937371-A1 A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM SABIC Global Technologies B.V. (NL) 2015-10-28 EP claimed
EP-2937372-A1 A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM SABIC Global Technologies B.V. (NL) 2015-10-28 EP claimed
EP-3445748-B1 METHODS OF MANUFACTURE OF 2-ARYL-3,3-BIS(4-HYDROXYARYL) PHTHALIMIDINES AND POLYMERS DERIVED THEREFROM SHPP GLOBAL TECH BV (NL) 2022-06-15 EP disclosed
EP-3129423-B1 A SYSTEM AND PROCESS FOR PRODUCING VARIOUS MOLECULAR WEIGHT MELT POLYCARBONATES SABIC GLOBAL TECHNOLOGIES BV (NL) 2022-05-25 EP disclosed
US-11078212-B2 2-hydrocarbyl-3-(dihydroxyfluoresceinyl)phthalimidine monomers, methods of manufacture, and copolymers derived therefrom SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2021-08-03 US disclosed
EP-3262098-B1 CONTROL OF ORGANIC IMPURITIES IN POLYCARBONATE SYNTHESIS SABIC GLOBAL TECHNOLOGIES BV (NL) 2021-06-16 EP disclosed
EP-3063202-B1 MELT POLYMERIZATION POLYCARBONATE QUENCHING SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-12-02 EP disclosed
US-10662154-B2 Methods of manufacture of 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidines, and polymers derived therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2020-05-26 US disclosed
EP-2937372-B1 A METHOD OF MELT POLYMERIZING POLYCARBONATE AND POLYCARBONATES DERIVED THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2020-04-22 EP disclosed
CN-110746341-A Method for purifying 2-aryl-3, 3-bis (4-hydroxyaryl) phthalimidines and polymers derived therefrom 沙特基础工业全球技术有限公司 2020-02-04 CN disclosed
US-5670605-A MELT COPOLYMERIZATION DIHYDROXYAROMATIC COMPOUNDS TO FORM POLYMERS GENERAL ELECTRIC COMPANY (US) 1997-09-23 US disclosed
US-5646233-A HAVING OUTSTANDING HARDNESS GENERAL ELECTRIC COMPANY (US) 1997-07-08 US disclosed
US-5606008-A MELT CONDENSATION POLYMERIZATION OF AROMATIC DIHYDROXY COMPOUND AND ESTER IN THE PRESENCE OF ALIPHATIC AMINE AND ALKALI OR ALKALINE EARTH METAL COMPOUND GENERAL ELECTRIC COMPANY (US) 1997-02-25 US disclosed
EP-0736574-A2 Thermoplastic resin composition comprising carbonate and acrylic resin GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0736561-A2 Dihydroxy compound mixtures and polymers thereof GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0719812-A2 Copolycarbonate GENERAL ELECTRIC COMPANY (US) 1996-07-03 EP disclosed
EP-0719813-A2 Copolycarbonate GENERAL ELECTRIC COMPANY (US) 1996-07-03 EP disclosed
EP-0694572-A2 A method for manufacturing polycarbonate GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed
EP-0694582-A2 A glass-fiber-reinforced polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11078212-B2 2-hydrocarbyl-3-(dihydroxyfluoresceinyl)phthalimidine monomers, methods of manufacture, and copolymers derived therefrom DPYD, DHFR, P4HTM CA1 2834/4885CA2 1551/4885LTA4H 2167/4885
US-10662154-B2 Methods of manufacture of 2-aryl-3,3-bis(4-hydroxyaryl)phthalimidines, and polymers derived therefrom PBRM1, PAH, PHF2 CA1 3272/4885CA2 660/4885LTA4H 2789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.