Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 4/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | BRD1 | O95696 | 1/20 | 0.33 |
| ▸ | TAF1 | P21675 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143411 | 0.84 | TDO2 (0.39) | TDO2IDO2IDO1NTRK1KMT2A | |
| SCHEMBL143252 | 0.83 | TDO2 (0.39) | TDO2IDO2IDO1NTRK1KMT2A | |
| SCHEMBL143408 | 0.82 | NTRK1 (0.40) | NTRK1KMT2AMEN1 | |
| SCHEMBL143247 | 0.80 | IDO1 (0.45) | TDO2IDO2IDO1NTRK1KMT2A | |
| SCHEMBL143891 | 0.70 | DNMT1 (0.38) | TDO2IDO2IDO1KMT2ARAB9A | |
| SCHEMBL142587 | 0.69 | KMT2A (0.40) | NTRK1KDM4EKMT2ARAB9AMEN1 | |
| SCHEMBL25822533 | 0.69 | KDM4E (0.48) | KDM4ENQO2KMT2ATSHRHSD17B10 | |
| SCHEMBL29930277 | 0.68 | NTRK1 (0.49) | TDO2IDO2IDO1NTRK1KMT2A | |
| SCHEMBL154140 | 0.68 | NTRK1 (0.49) | TDO2IDO2IDO1NTRK1KMT2A | |
| SCHEMBL152432 | 0.68 | IDO1 (0.55) | TDO2IDO2IDO1NTRK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |