Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.34 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | NCEH1 | Q6PIU2 | 3/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143411 | 0.77 | TDO2 (0.39) | CYP1A2CYP2C9CYP2C19POLBIDO1 | |
| SCHEMBL143247 | 0.75 | IDO1 (0.45) | CES1POLBIDO1TDO2IDO2 | |
| SCHEMBL142587 | 0.75 | KMT2A (0.40) | TDP1RAB9ASMN1; SMN2HPGDHTT | |
| SCHEMBL24051212 | 0.73 | TDO2 (0.49) | DNMT1IDO1TDO2IDO2RAB9A | |
| SCHEMBL25725086 | 0.71 | POLB (0.47) | TDP1CYP1A2CYP2C9CYP2C19POLB | |
| SCHEMBL140840 | 0.70 | TDO2 (0.39) | POLBIDO1TDO2IDO2CDK5 | |
| SCHEMBL143252 | 0.70 | TDO2 (0.39) | IDO1TDO2IDO2CDK5CDK5R1 | |
| SCHEMBL30884623 | 0.67 | DNMT1 (0.40) | DNMT1TDP1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL155403 | 0.67 | IDO1 (0.34) | CYP2C19IDO1TDO2IDO2SMN1; SMN2 | |
| SCHEMBL143408 | 0.67 | NTRK1 (0.40) | HTTMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |