Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 4/20 | 0.39 |
| ▸ | IDO2 | Q6ZQW0 | 4/20 | 0.39 |
| ▸ | IDO1 | P14902 | 3/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL143411 | 0.87 | TDO2 (0.39) | TDO2IDO2IDO1HSP90AA1APAF1 | |
| SCHEMBL140840 | 0.83 | TDO2 (0.39) | TDO2IDO2IDO1HSP90AA1APAF1 | |
| SCHEMBL143247 | 0.80 | IDO1 (0.45) | TDO2IDO2IDO1NPC1RAB9A | |
| SCHEMBL143408 | 0.80 | NTRK1 (0.40) | MEN1KMT2ANTRK1GSK3B | |
| SCHEMBL143891 | 0.70 | DNMT1 (0.38) | TDO2IDO2IDO1MEN1NPC1 | |
| SCHEMBL9103165 | 0.68 | IDO1 (0.74) | TDO2IDO2IDO1HSP90AA1APAF1 | |
| SCHEMBL142587 | 0.66 | KMT2A (0.40) | MEN1RAB9AKMT2ANTRK1L3MBTL1 | |
| SCHEMBL152432 | 0.62 | IDO1 (0.55) | TDO2IDO2IDO1APAF1MEN1 | |
| SCHEMBL3408954 | 0.62 | IDO1 (0.55) | TDO2IDO2IDO1HSP90AA1APAF1 | |
| SCHEMBL22771502 | 0.62 | ALDH1A1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| US-8940909-B2 | Indicator platform | BIOSYNTH AG (CH) | 2015-01-27 | — | — | US | disclosed |
| EP-2427431-B1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2013-05-01 | — | — | EP | disclosed |
| US-20120058503-A1 | Novel Indicator Platform | BIOSYNTH AG (CH) | 2012-03-08 | — | — | US | disclosed |
| WO-2010128120-A1 | NOVEL INDICATOR PLATFORM | BIOSYNTH AG (CH) | 2010-11-11 | — | — | WO | disclosed |