SCHEMBL14084603

SCHEMBL14084603

O=C(O)CSc1nc(Cl)nc(Nc2cc(S(=O)(=O)O)cc3cc(SOOO)c(N=Nc4ccc(C(=O)CS(=O)(=S)OOO)cc4)c(O)c23)n1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ FUT8 Q9BYC5 1/20 0.39
▸ ENPP2 Q13822 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14020322 0.84 FUT8 (0.40) FUT8ENPP2
SCHEMBL14084601 0.79 FUT8 (0.36) FUT8ENPP2
SCHEMBL14084600 0.78 PHLPP2 (0.30) —
SCHEMBL14020350 0.77 FUT8 (0.43) FUT8
SCHEMBL14084619 0.75 FUT8 (0.46) FUT8ENPP2
SCHEMBL14020377 0.73 FUT8 (0.41) FUT8ENPP2
SCHEMBL14084618 0.73 FUT8 (0.44) FUT8ENPP2
SCHEMBL13839143 0.73 FUT8 (0.51) FUT8ENPP2
SCHEMBL13420796 0.73 FUT8 (0.43) FUT8ENPP2
SCHEMBL13599484 0.73 FUT8 (0.52) FUT8ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group EVERLIGHT USA, INC. (US) 2008-08-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080207881-A1 Reactive dyes containing an alkylthio-s-triazinyl reactive group TST, IK, NOX5 FUT8 672/4885ENPP2 2713/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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