SCHEMBL140863

SCHEMBL140863

C=C(C)OC(=O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.56
LMNA P02545 3/20 0.54
F2 P00734 1/20 0.54
TDP1 Q9NUW8 4/20 0.47
ALDH1A1 P00352 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CES2 O00748 1/20 0.46
CES1 P23141 1/20 0.46
SLC6A3 Q01959 2/20 0.46
TP53 P04637 1/20 0.45
ELANE P08246 2/20 0.44
MAPT P10636 3/20 0.44
KMT2A Q03164 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPK1 P28482 1/20 0.44
HIF1A Q16665 1/20 0.44
POLB P06746 1/20 0.44
SLC6A2 P23975 1/20 0.44
XBP1 P17861 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5450979 0.89 TDP1 (0.48) TSHRLMNAF2TDP1ALDH1A1
Methacrylic Acid SCHEMBL777587 0.85 TSHR (0.54) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL9008922 0.85 TDP1 (0.41) TSHRTDP1ALDH1A1HSD17B10CES2
SCHEMBL6904760 0.85 TSHR (0.50) TSHRTDP1ALDH1A1HSD17B10TP53
Acetic Acid SCHEMBL777098 0.84 TSHR (0.62) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL28514832 0.83 ELANE (0.54) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL22880269 0.83 TSHR (0.52) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL777588 0.83 ELANE (0.54) TSHRLMNAF2TDP1ALDH1A1
SCHEMBL9008994 0.83 CA12 (0.46) LMNATDP1ALDH1A1HSD17B10MAPT
SCHEMBL17892405 0.83 CA12 (0.46) LMNATDP1ALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 946 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119585437-A Eribulin Process for the preparation of intermediates 上海皓元医药股份有限公司 2025-03-07 CN claimed
CN-118742210-A Chocolate replicas made from multiple individual components 航行食品股份有限公司 2024-10-01 CN claimed
CN-111799507-B Polymer electrolyte composite membrane and preparation method thereof 浙江锋锂新能源科技有限公司 2023-11-14 CN claimed
CN-115323011-A Preparation method of eribulin intermediate 上海皓元医药股份有限公司 2022-11-11 CN claimed
US-20170298026-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2017-10-19 US claimed
EP-3204353-A1 ALL PURPOSE RAFT AGENT Commonwealth Scientific and Industrial Research Organisation (AU) 2017-08-16 EP claimed
US-20170088703-A9 COMPATIBILIZER BASED ON INTERPENETRATING POLYMER NETWORKS (IPN) FOR RECYCLING POLYMER BLENDS Instituto Potosino De Investigacion Cientifica y Tecnologica A.C. (MX) 2017-03-30 US claimed
US-20160340463-A1 PROCESS FOR PREPARING A POLYMER NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2016-11-24 US claimed
WO-2016054689-A1 ALL PURPOSE RAFT AGENT COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 2016-04-14 WO claimed
US-20150225562-A1 COMPATIBILIZER BASED ON INTERPENETRATING POLYMER NETWORKS (IPN) FOR RECYCLING POLYMER BLENDS ESCOBAR BARRIOS VLADIMIR ALONSO (MX) 2015-08-13 US claimed
EP-0338486-A2 Stable emulsion polymers and methods of preparing same S.C. JOHNSON & SON, INC. (US) 1989-10-25 EP claimed
EP-0140648-B1 HYDROGEN PEROXIDE COMPOSITIONS Interox Chemicals Limited (GB) 1989-03-01 EP claimed
EP-0122763-B1 BLEACH COMPOSITIONS Interox Chemicals Limited (GB) 1987-06-16 EP claimed
US-4613452-A BLEACH OR DISINFECTANT INTEROX CHEMICALS LIMITED (GB) 1986-09-23 US claimed
EP-0092932-B1 HYDROGEN PEROXIDE COMPOSITIONS Interox Chemicals Limited (GB) 1986-05-28 EP claimed
US-4545784-A LOW-TEMPERATURE ACTIVATED BLEACHES; LAUNDERING; ANTISEPTICS; STORAGE STABILITY INTEROX CHEMICALS LIMITED (GB) 1985-10-08 US claimed
EP-0140648-A2 Hydrogen peroxide compositions Interox Chemicals Limited (GB) 1985-05-08 EP claimed
US-4496473-A BLEACHES, DISINFECTANTS INTEROX CHEMICALS LIMITED (GB) 1985-01-29 US claimed
EP-0122763-A2 Bleach compositions Interox Chemicals Limited (GB) 1984-10-24 EP claimed
EP-0092932-A1 Hydrogen peroxide compositions Interox Chemicals Limited (GB) 1983-11-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170298026-A1 ALL PURPOSE RAFT AGENT NPC1L1, RFTN1, SGMS2 TSHR 4058/4885LMNA 759/4885F2 1563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.