Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.67 |
| ▸ | THRB | P10828 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438151 | 0.85 | MAPT (0.80) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL21916975 | 0.85 | MAPT (0.75) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL1408653 | 0.84 | KDM4E (0.68) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL2401558 | 0.83 | MAPT (0.76) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL4620865 | 0.82 | MAPT (0.78) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL80364 | 0.80 | MAPT (1.00) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL29493002 | 0.80 | MAPT (1.00) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL13839771 | 0.80 | MAPT (1.00) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL14077718 | 0.80 | KDM4E (0.59) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 | |
| SCHEMBL13619846 | 0.78 | MAPT (0.69) | MAPTKDM4ETHRBSMN1; SMN2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1560060-B1 | Polarizing or photochromic plastic lens, coated sheet-like light element and method of its production | MGC FILSEET CO LTD (JP) | 2011-03-09 | — | — | EP | disclosed |
| US-7350917-B2 | Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens | MGC FILSEET CO., LTD. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20050168690-A1 | Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens | FUJI KASEI CO., LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1560060-A1 | Polarizing or photochromic plastic lens, coated sheet-like light element and method of its production | Fuji Kasei Co., Ltd. (JP) | 2005-08-03 | — | — | EP | disclosed |