SCHEMBL1409003

SCHEMBL1409003

O=C1OPOc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.40
ALOX15 P16050 1/20 0.40
PKM P14618 1/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
CDC25B P30305 2/20 0.38
KDM4E B2RXH2 3/20 0.36
POLB P06746 2/20 0.36
MAOA P21397 2/20 0.36
CES1 P23141 2/20 0.36
LMNA P02545 2/20 0.36
CES2 O00748 1/20 0.36
APAF1 O14727 1/20 0.36
TERT O14746 1/20 0.36
NPC1 O15118 1/20 0.36
PLIN1 O60240 1/20 0.36
TDP2 O95551 1/20 0.36
S1PR4 O95977 1/20 0.36
PLA2G1B P04054 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2583969 0.76
SCHEMBL30058027 0.76 ABCG2 (0.40) TDP1TSHRMAOALMNAHTT
SCHEMBL30559479 0.74 POLB (0.36) ALOX15TSHRMEN1KMT2AKDM4E
SCHEMBL19754922 0.69 TDP1 (0.63) TDP1ALOX15PKMTSHRMEN1
SCHEMBL30320031 0.69 TDP1 (0.63) TDP1ALOX15PKMTSHRMEN1
SCHEMBL167093 0.69
SCHEMBL12691224 0.69 TDP1 (0.63) TDP1ALOX15PKMTSHRMEN1
SCHEMBL30567320 0.67 TDP1 (0.68) TDP1ALOX15PKMTSHRMEN1
SCHEMBL259173 0.66 CES1 (0.36) TDP1MEN1KMT2ACES1MAPT
SCHEMBL29669461 0.66 ABCG2 (0.36) MAOALMNAHTTSMN1; SMN2MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4486717-A1 PROCESS FOR PREPARING GAMMA,DELTA-UNSATURATED ALDEHYDES DERIVATIVES Firmenich SA (CH) 2025-01-08 EP disclosed
WO-2023166004-A1 PROCESS FOR PREPARING GAMMA,DELTA-UNSATURATED ALDEHYDES DERIVATIVES FIRMENICH SA (CH) 2023-09-07 WO disclosed
US-20160280732-A1 MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2016-09-29 US disclosed
WO-2016147185-A1 ADENOSINE THIOPHOSPHATE DERIVATIVES AND USES THEREOF BAR-ILAN UNIVERSITY (IL) 2016-09-22 WO disclosed
US-8049041-B2 Phosphite stabilizer for lubricating base stocks and thermoplastic polymers CHEMTURA CORPORATION (US) 2011-11-01 US disclosed
EP-2294074-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS Chemtura Corporation (US) 2011-03-16 EP disclosed
US-20100016196-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS CHEMTURA CORPORATION 2010-01-21 US disclosed
WO-2009158078-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS CHEMTURA CORPORATION (US) 2009-12-30 WO disclosed
EP-1586577-A1 Novel phosphite compounds and novel phosphite metal complexes Oxeno Olefinchemie GmbH (DE) 2005-10-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100016196-A1 PHOSPHITE STABILIZER FOR LUBRICATING BASE STOCKS AND THERMOPLASTIC POLYMERS PHOSPHO1, PLCG2, PLPBP TDP1 573/4885ALOX15 341/4885PKM 1230/4885
US-20160280732-A1 MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF RDX, RPS4X, MLX TDP1 3442/4885ALOX15 3509/4885PKM 1923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.