SCHEMBL29669461

SCHEMBL29669461

c1ccc2c(c1)OPOPO2

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.36
ITGB2 P05107 1/20 0.36
ICAM1 P05362 1/20 0.36
ITGAL P20701 1/20 0.36
LMNA P02545 2/20 0.32
CRHBP P24387 2/20 0.32
CRHR2 Q13324 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
ALOX5 P09917 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
HTT P42858 1/20 0.32
AHR P35869 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30058027 0.87 ABCG2 (0.40) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL2583969 0.87
SCHEMBL30060480 0.72 ADRA2A (0.34)
SCHEMBL3889563 0.67 MAOA (0.61) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL29538767 0.67 MAOA (0.61) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL9132002 0.67 MAOA (0.37) ABCG2ITGB2ICAM1ITGALMAOA
SCHEMBL1409003 0.66 TDP1 (0.40) LMNASMN1; SMN2MAOAMAOBHTT
SCHEMBL6237669 0.64 MAOA (0.37) MAOAMAOB
SCHEMBL3102452 0.60 MAOA (0.56) ABCG2ITGB2ICAM1ITGALLMNA
SCHEMBL125113 0.60 MAOA (0.56) ABCG2ITGB2ICAM1ITGALLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114479400-A PC/ABS alloy material and preparation method and application thereof 中国石油化工股份有限公司 2022-05-13 CN disclosed