Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14583982 | 0.83 | GPR142 (0.45) | GPR142LMNA | |
| SCHEMBL6248354 | 0.83 | TSHR (0.50) | ALDH1A1CYP3A4GPR142AKT1TSHR | |
| SCHEMBL6248350 | 0.83 | TSHR (0.50) | ALDH1A1CYP3A4GPR142AKT1TSHR | |
| Hydrochloric Acid SCHEMBL7894482 | 0.81 | TSHR (0.49) | ALDH1A1CYP3A4GPR142AKT1TSHR | |
| SCHEMBL14090288 | 0.80 | GRIA1 (0.41) | GPR142 | |
| SCHEMBL13073337 | 0.80 | SMN1; SMN2 (0.58) | ALDH1A1CYP3A4 | |
| SCHEMBL13496530 | 0.77 | ALPI (0.51) | — | |
| SCHEMBL21010316 | 0.76 | SLC15A1 (0.64) | CYP3A4TSHR | |
| SCHEMBL12992547 | 0.76 | HSD17B10 (0.47) | ALDH1A1CYP3A4GPR142AKT1TSHR | |
| SCHEMBL14338226 | 0.76 | HSD17B10 (0.47) | ALDH1A1CYP3A4GPR142AKT1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417030-B2 | Indazole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-7183252-B2 | Indole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2007-02-27 | — | — | US | disclosed |