Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 20/20 | 0.68 |
| ▸ | F2 | P00734 | 2/20 | 0.61 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14090286 | 0.94 | F2R (0.68) | F2RF2F2RL1 | |
| Rwj-58259 SCHEMBL14090275 | 0.87 | F2R (0.83) | F2RF2F2RL1 | |
| SCHEMBL14090284 | 0.83 | F2R (0.76) | F2RF2F2RL1 | |
| SCHEMBL14583983 | 0.83 | F2R (0.82) | F2RF2 | |
| SCHEMBL14090282 | 0.80 | F2R (0.74) | F2RF2F2RL1 | |
| SCHEMBL14583992 | 0.79 | F2R (0.67) | F2RF2 | |
| SCHEMBL4263176 | 0.74 | F2R (0.85) | F2RF2 | |
| SCHEMBL14614228 | 0.73 | F2R (0.47) | F2RF2 | |
| SCHEMBL14583978 | 0.71 | F2R (0.77) | F2RF2 | |
| SCHEMBL14583985 | 0.69 | F2R (0.52) | F2RF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7417030-B2 | Indazole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-08-26 | — | — | US | disclosed |
| US-7417030-B2 | Indazole peptidomimetics as thrombin receptor antagonists | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2008-08-26 | — | — | US | disclosed |