Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 5/20 | 0.56 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4986287 | 0.86 | IDO1 (0.46) | BACE1LMNAMAPT | |
| SCHEMBL16763522 | 0.83 | MGLL (0.55) | BACE1PPARGSYKMGLLMEN1 | |
| SCHEMBL16763519 | 0.83 | MGLL (0.55) | BACE1PPARGSYKMGLLMEN1 | |
| SCHEMBL6549737 | 0.82 | PPARG (0.59) | BACE1PPARGSYKMGLL | |
| SCHEMBL6548418 | 0.82 | PPARG (0.62) | BACE1PPARGSYKMGLL | |
| SCHEMBL6548407 | 0.82 | PPARG (0.62) | BACE1PPARGSYKMGLL | |
| SCHEMBL7021124 | 0.82 | MAPT (0.55) | BACE1SYKLMNAMAPTHTT | |
| SCHEMBL7021126 | 0.82 | MAPT (0.55) | BACE1SYKLMNAMAPTHTT | |
| SCHEMBL27983817 | 0.81 | KMT2A (0.51) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2367199 | 0.80 | ITGB3 (0.60) | BACE1SYKMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | ENCYSIVE PHARMACEUTICALS, INC. | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188528-A1 | Modulators of C3a receptor and methods of use thereof | C3AR1, C5, C5AR1 | BACE1 1614/4885PPARG 2064/4885SYK 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.