Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 4/20 | 0.57 |
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6548407 | 1.00 | PPARG (0.62) | PPARGBACE1MGLLSYKENPP2 | |
| SCHEMBL6549737 | 0.94 | PPARG (0.59) | PPARGBACE1MGLLSYKENPP2 | |
| SCHEMBL16763519 | 0.88 | MGLL (0.55) | PPARGBACE1MGLLSYKENPP2 | |
| SCHEMBL16763522 | 0.88 | MGLL (0.55) | PPARGBACE1MGLLSYKENPP2 | |
| SCHEMBL6897765 | 0.84 | CTSS (0.62) | PPARGBACE1SYK | |
| SCHEMBL14090974 | 0.82 | BACE1 (0.56) | PPARGBACE1MGLLSYK | |
| SCHEMBL23837230 | 0.81 | CTSS (0.60) | PPARGBACE1SYK | |
| SCHEMBL17724519 | 0.81 | CTSS (0.60) | PPARGBACE1SYK | |
| SCHEMBL7561033 | 0.81 | CTSS (0.51) | PPARGBACE1SYK | |
| SCHEMBL23619660 | 0.81 | CTSS (0.51) | PPARGBACE1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142317-A1 | Use of amino acid transporter atbo,+ as a delivery system for drugs and prodrugs | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-07-22 | — | — | US | disclosed |
| EP-1384081-A2 | USE OF AMINO ACID TRANSPORTER ATB0,+ AS A DELIVERY SYSTEM FOR DRUGS AND PRODRUGS | Medical College Of Georgia Research Institute, Inc. (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002083060-A2 | USE OF AMINO ACID TRANSPORTER ATB0,+ AS A DELIVERY SYSTEM FOR DRUGS AND PRODRUGS | MEDICAL COLLEGE OF GEORGIA RESEARCH INSTITUTE, INC. (US) | 2002-10-24 | — | — | WO | disclosed |