Nojirimycin

Nojirimycin

SCHEMBL140917

OC[C@H]1NC(O)[C@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
FUCA1 P04066 7/20 0.74
MGAM O43451 5/20 0.74
GLA P06280 3/20 0.74
GANC Q8TET4 2/20 0.74
GAA P10253 2/20 0.74
AGL P35573 2/20 0.68
GBA2 Q9HCG7 1/20 0.68
GBA1 P04062 1/20 0.68
FUCA2 Q9BTY2 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nojirimycin SCHEMBL24518012 1.00 FUCA1 (0.74) FUCA1MGAMGLAGANCGAA
Nojirimycin SCHEMBL18819521 1.00 FUCA1 (0.74) FUCA1MGAMGLAGANCGAA
Nojirimycin SCHEMBL11239684 1.00 FUCA1 (0.74) FUCA1MGAMGLAGANCGAA
Nojirimycin SCHEMBL25084034 1.00 FUCA1 (0.74) FUCA1MGAMGLAGANCGAA
Nojirimycin SCHEMBL20470306 1.00 FUCA1 (0.74) FUCA1MGAMGLAGANCGAA
SCHEMBL7824407 0.85 MGAM (1.00) FUCA1MGAMGLAGANCGAA
SCHEMBL7811568 0.85 MGAM (1.00) FUCA1MGAMGLAGANCGAA
SCHEMBL2265531 0.85 MGAM (1.00) FUCA1MGAMGLAGANCGAA
SCHEMBL18271004 0.85 MGAM (1.00) FUCA1MGAMGLAGANCGAA
SCHEMBL1879685 0.85 MGAM (1.00) FUCA1MGAMGLAGANCGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1408 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025137203-A1 GLUCOSE OXIDASE SENSORS WITH IMPROVED STABILITY ABBOTT DIABETES CARE, INC. (US) 2025-06-26 WO claimed
US-20250194964-A1 GLUCOSE OXIDASE SENSORS WITH IMPROVED STABILITY ABBOTT DIABETES CARE, INC. 2025-06-19 US claimed
WO-2025083657-A1 LIPID COMPOUND AND COMPOSITION FOR TISSUE-SPECIFIC DELIVERY OF ACTIVE SUBSTANCE 한국생명공학연구원 2025-04-24 WO claimed
CN-112689758-B Device and method for checking the effect of a drug on microorganisms 上海宜晟生物科技有限公司 2025-03-28 CN claimed
CN-115838350-B Method for simultaneously preparing deoxynojirimycin, chlorogenic acid and morin from cortex mori 陕西嘉禾药业有限公司 2025-03-04 CN claimed
CN-118202061-A Method of treating fabry disease using viral vector constructs 桑格摩生物治疗股份有限公司 2024-06-14 CN claimed
CN-116926030-A Transaminase mutant and application thereof 中国科学院天津工业生物技术研究所 2023-10-24 CN claimed
CN-116710185-A Highly purified batches of pharmaceutical grade 1-deoxygalactonojirimycin compounds 阿米库斯治疗学公司 2023-09-05 CN claimed
US-20230192748-A1 Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug DOUBLERAINBOW BIOSCIENCES INC. 2023-06-22 US claimed
US-20230193336-A1 ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION DOUBLERAINBOW BIOSCIENCES INC. 2023-06-22 US claimed
US-4908439-A Synthesis of intermediate useful in the preparation of nojirimycin and related compounds MERRELL DOW PHARMACEUTICALS INC. (US) 1990-03-13 US claimed
EP-0344383-A1 Novel alpha-Glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1989-12-06 EP claimed
EP-0345104-A2 Novel Alpha-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1989-12-06 EP claimed
EP-0319986-A2 Fibrinolytic agents NIPPON SHINYAKU COMPANY, LIMITED (JP) 1989-06-14 EP claimed
EP-0189461-A4 METHOD OF DETERMINING CYSTIC FIBROSIS CILIOSTATIC FACTOR. COOPERBIOMEDICAL INC (US) 1988-05-10 EP claimed
US-4673633-A Method of determining cystic fibrosis ciliostatic factor COOPERBIOMEDICAL, INC. (US) 1987-06-16 US claimed
EP-0189461-A1 METHOD OF DETERMINING CYSTIC FIBROSIS CILIOSTATIC FACTOR. COOPERBIOMEDICAL INC (US) 1986-08-06 EP claimed
WO-1986000343-A1 METHOD OF DETERMINING CYSTIC FIBROSIS CILIOSTATIC FACTOR COOPERBIOMEDICAL, INC. (US) 1986-01-16 WO claimed
US-4339585-A Method for the production of 2-hydroxymethyl-3,4,5-trihydroxy piperidine and the corresponding N-methyl derivative NIPPON SHINYAKU CO., LTD. (JP) 1982-07-13 US claimed
US-4064277-A SOYBEAN MILK, BETA-GLYCOSIDASE KIKKOMAN SHOYU CO., LTD. (JA) 1977-12-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230193336-A1 ENASIDENIB GLYCOSIDES AND METHODS OF TREATING DISEASES ASSOCIATED WITH ISOCITRATE DEHYDROGENASE (IDH) DYSFUNCTION UGDH, IDH1, G6PD FUCA1 31/4885MGAM 73/4885GLA 98/4885
US-20230192748-A1 Etoposide Glycosides, Methods Of Making, And Uses Thereof As An Anti-Cancer Drug GALE, UGGT1, DERA FUCA1 8/4885MGAM 43/4885GLA 112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.