Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13958885 | 0.88 | KDM4E (0.57) | ALDH1A1KDM4EHTTSMN1; SMN2FFAR1 | |
| SCHEMBL13958863 | 0.87 | MMP13 (0.52) | ALDH1A1KDM4EHTTSMN1; SMN2FAAH | |
| SCHEMBL13958845 | 0.87 | ALDH1A1 (0.65) | ALDH1A1KDM4EHTTSMN1; SMN2FFAR1 | |
| SCHEMBL13958879 | 0.85 | ALDH1A1 (0.51) | ALDH1A1KDM4EHTTSMN1; SMN2FAAH | |
| SCHEMBL16316303 | 0.81 | FDFT1 (0.50) | ALDH1A1KDM4EHTTSMN1; SMN2FAAH | |
| SCHEMBL13958862 | 0.81 | HTR2A (0.45) | ALDH1A1KDM4EHTTSMN1; SMN2FAAH | |
| SCHEMBL13958859 | 0.81 | MAPK14 (0.49) | ALDH1A1KDM4ESMN1; SMN2FAAHFDFT1 | |
| SCHEMBL4178678 | 0.80 | FDFT1 (0.49) | ALDH1A1KDM4EHTTSMN1; SMN2FAAH | |
| SCHEMBL4178681 | 0.80 | ALDH1A1 (0.51) | ALDH1A1KDM4EHTTSMN1; SMN2FAAH | |
| SCHEMBL13802648 | 0.80 | FAAH (0.49) | ALDH1A1KDM4EHTTSMN1; SMN2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |