SCHEMBL14093931

SCHEMBL14093931

CN(O)C(=O)Nc1cc(NC(=O)CCC(=O)Nc2cc(NC(=O)N(C)O)cc(-n3c(S)nnc3S)c2)cc(-n2c(S)nnc2S)c1

nearest known ligand 0.35

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ TERT O14746 8/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ KMT2A Q03164 1/20 0.32
▸ HDAC3 O15379 2/20 0.31
▸ HDAC4 P56524 2/20 0.31
▸ HDAC1 Q13547 2/20 0.31
▸ HDAC7 Q8WUI4 2/20 0.31
▸ HDAC2 Q92769 2/20 0.31
▸ HDAC10 Q969S8 2/20 0.31
▸ HDAC11 Q96DB2 2/20 0.31
▸ HDAC8 Q9BY41 2/20 0.31
▸ HDAC6 Q9UBN7 2/20 0.31
▸ HDAC9 Q9UKV0 2/20 0.31
▸ HDAC5 Q9UQL6 2/20 0.31
▸ LMNA P02545 1/20 0.31
▸ RORC P51449 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14093922 0.92 GAA (0.38) GAA
SCHEMBL14360913 0.81 GAA (0.32) GAA
SCHEMBL13656906 0.79 POLB (0.42) GAAKMT2AHDAC6
SCHEMBL13656912 0.78 GAA (0.48) L3MBTL1GAAKMT2ALMNA
SCHEMBL17153764 0.71 GAA (0.41) L3MBTL1GAAKMT2A
SCHEMBL14093856 0.71 POLB (0.36) KMT2ALMNA
SCHEMBL14093908 0.69 POLB (0.42) TERTKMT2AHDAC3HDAC1HDAC2
SCHEMBL14093924 0.69 GAA (0.32) GAA
SCHEMBL14359778 0.68 TERT (0.46) TERTGAAKMT2AHDAC3HDAC4
SCHEMBL14093868 0.66 CNR1 (0.39) L3MBTL1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410745-B2 Photothermographic material and image forming method using same FUJIFILM CORPORATION (JP) 2008-08-12 — — US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 — — US disclosed
US-7303864-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2007-12-04 — — US disclosed
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