SCHEMBL1409436

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21690688	0.88	DUT (0.63)	DUTALDH1A1LMNAPOLBRORA
	SCHEMBL12630519	0.85	DUT (0.66)	DUTALDH1A1LMNAPOLBRORA
	SCHEMBL1409352	0.83	DUT (0.67)	DUT
	SCHEMBL12629721	0.83	DUT (0.67)	DUTALDH1A1LMNAPOLBMAPT
	SCHEMBL1409455	0.82	DUT (0.56)	DUTALDH1A1KEAP1MAPTGAA
	SCHEMBL1408963	0.78	DUT (1.00)	DUT
	SCHEMBL11209446	0.77	LMNA (0.65)	DUTALDH1A1LMNAPOLBRORA
	SCHEMBL27827503	0.75	DUT (0.65)	DUT
	SCHEMBL24926381	0.75	PARG (0.55)	DUTALDH1A1LMNAPOLBRORA
	SCHEMBL24927353	0.73	DUT (0.56)	DUTALDH1A1LMNAPOLBRORA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.