SCHEMBL1409455

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27827531	0.88	DUT (0.54)	DUTCYP2C19NAMPTNR3C2ALDH1A1
	SCHEMBL21690373	0.85	DUT (0.56)	DUTCYP2C19NAMPTNR3C2ALDH1A1
	SCHEMBL6903823	0.84	NR3C2 (0.53)	DUTCYP2C19NAMPTNR3C2ALDH1A1
	SCHEMBL1409436	0.82	DUT (0.63)	DUTALDH1A1GAAMAPTSMN1; SMN2
	SCHEMBL9765329	0.80	MEN1 (0.51)	DUTCYP2C19NAMPTNR3C2ALDH1A1
	SCHEMBL10448561	0.80	KEAP1 (0.53)	DUTCYP2C19NR3C2ALDH1A1ATM
	SCHEMBL1458716	0.77	ALDH1A1 (0.54)	CYP2C19NAMPTALDH1A1MAPTKDM4E
	SCHEMBL12630519	0.77	DUT (0.66)	DUTALDH1A1GAAMAPTKDM4E
	SCHEMBL1409352	0.75	DUT (0.67)	DUTNAMPT
	SCHEMBL12629721	0.75	DUT (0.67)	DUTALDH1A1MAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.