Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.41 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.41 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8233885 | 0.82 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1HTR3EHTR3B | |
| SCHEMBL14127817 | 0.81 | KDM4E (0.55) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL4847221 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL5765507 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL6233656 | 0.80 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL5936119 | 0.79 | MAPT (0.46) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL6271582 | 0.79 | HTR3E (0.45) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL14125084 | 0.77 | KDM4E (0.45) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL31434444 | 0.75 | MAPT (0.48) | ALDH1A1SMN1; SMN2HTR3EHTR3BCYP1A2 | |
| SCHEMBL27459309 | 0.75 | ALDH1A1 (0.44) | ALDH1A1HTR3EHTR3BCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7408025-B2 | Lipopeptides as antibacterial agents | CUBIST PHARMACEUTICALS, INC. (US) | 2008-08-05 | — | — | US | disclosed |